Having Hypertension (high blood pressure) is considered to be one of the most significant risk factors for cardiovascular disease. With an estimated nearly 15 million people in the UK, just over a quarter of all adults, having hypertension, research into ongoing treatments for hypertension is so important.
This study is investigating how effective the study treatment is, in combination with standard of care treatments, at reducing the risk of major heart events in patients who have Hypertension that is not adequately controlled and are either living with Cardiovascular Disease or are at high risk of Cardiovascular Disease.
If you have hypertension that is not adequately controlled, this research study could be of interest to you.






This study is open to anyone who:
Has uncontrolled blood pressure or uncontrolled hypertension
And
Is over the age of 18 and living with established Cardiovascular Disease (Previously experienced a Heart Attack, Stroke, or has Peripheral Artery Disease)
Or
Is 55 years old or older and is at high risk of developing Cardiovascular Disease due to:
- Being over the age of 70
- Being a current smoker
- Or living with Type 1 or Type 2 Diabetes
Other inclusion / exclusion criteria will apply and this will be discussed with you by one of our research team over the phone.
Participation in the study will last for between 2.5 to 5 years and involves receiving the study treatment, or placebo, once every 6 months. This study is placebo-controlled meaning half of participants will receive the study treatment and the other half will receive a placebo.
Participation will also involve regular visits to our clinic throughout the course of the study.
You will receive reimbursement for your study related time and activities, such as visits to our clinic.
Participation in clinical trials provides access to innovative and potentially life-saving treatments. It also contributes to medical research, benefiting both current and future healthcare outcomes. It provides cutting-edge medical care under professional supervision and empowers individuals to contribute to the well-being of society. However, participants should carefully weigh up the risks and benefits and seek advice from their doctor before taking part in a trial.